Natural killer cells regulate Th1/Treg and Th17/Treg balance in chlamydial lung infection
نویسندگان
چکیده
منابع مشابه
Natural killer cells regulate Th1/Treg and Th17/Treg balance in chlamydial lung infection
Natural killer (NK) cell is an important component in innate immunity, playing a critical role in bridging innate and adaptive immunity by modulating the function of other immune cells including T cells. In this study, we focused on the role of NK cells in regulating Th1/Treg and Th17/Treg balance during chlamydial lung infection. We found that NK cell-depleted mice showed decreased Th1 and Th1...
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متن کاملNatural killer T cells are critical for dendritic cells to induce immunity in Chlamydial pneumonia.
RATIONALE We previously showed an important role of natural killer T cells (NKT) in skewing the adaptive T cell immunity to Chlamydia pneumoniae (Cpn), an intracellular bacterial lung infection, but the mechanism remains unclear. OBJECTIVES To investigate the underlying mechanism by which NKT modulate T cell responses in chlamydial pneumonia. METHODS We examined the effect of NKT activation...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2016
ISSN: 1582-1838,1582-4934
DOI: 10.1111/jcmm.12821